Stereoselective reduction of ketones
US5391495A · kind A · utility
13Cited by
3References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 27, 1993 |
| Grant date | Feb 21, 1995 |
| Priority date | — |
| Expiry date | Oct 27, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/931
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention concerns a process for the stereoselective enzymatic reduction of keto group-containing compounds such as N-(4-(2-chloroacetyl)phenyl)methanesulfonamido to form the corresponding hydroxyl-group containing compound. The process is selective for the D(+) enantiomer and is catalyzed by enzymes such as oxido-reductase or dehydrogense, or by microorganisms such as Hansenula, Rhodococcus, or Norcardia species.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.