Cinnoline-3-carboxylic acid derivatives
US5391549A · kind A · utility
2Cited by
5References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 10, 1993 |
| Grant date | Feb 21, 1995 |
| Priority date | — |
| Expiry date | Mar 10, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D453/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel cinnoline derivative having an antagonistic activity against serotonin 5-HT.sub.3 receptor, its pharmaceutically acceptable salts, its N-oxide derivatives or solvates thereof, and pharmaceutical formulations containing the same for the prevention and/or treatment of various disorders such as nausea and/or emesis caused by anticancer drugs or X-ray treatment, central nervous disorders such as anxiety and/or neuropathy, gastroenteric diseases such as indigestion, chronic gastritis, digestive ulcer, irritable bowel syndromes and the like, hemicrania, cluster headache, trigeminal neuralgia, arrhythmia and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.