Process for the preparation of antiulcer agents
US5391752A · kind A · utility
40Cited by
6References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 22, 1993 |
| Grant date | Feb 21, 1995 |
| Priority date | — |
| Expiry date | Feb 22, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Anti-ulcer agents having a methylsulfinyl bridge between a substituted pyridine moiety and a substituted benzimidazole moiety are prepared by oxidizing the corresponding compounds, having a methylthio bridge, with magnesium monoperoxyphthalate in a suitable solvent. The reaction may be run in an aromatic hydrocarbon solvent, wherein the product may crystallize out of the reaction solution and may be directly isolated by filtration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.