Heterocyclic amide derivatives

US5391758A · kind A · utility

Assignee

• Zeneca Limited · GB

Inventors

• Peter Bernstein · Wallingford, US
• Frederick J. Brown · Newark, US
• Victor G. Matassa · Roma, IT
• Ying Kwong Yee · Kennett Square, US

Key dates

• Filing date: Jun 6, 1994
• Grant date: Feb 21, 1995
• Expiry date: Jun 6, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention concerns novel, pharmaceutically useful, amide derivatives of certain benzoheterocyclylalkanoic acids (and related tetrazoles and acylsulphonamides) of the formula I and salts thereof, wherein the radicals R.sup.1, R.sup.2, L, X, Y, Z, A.sup.1, Q, A.sup.2 and M have the meanings set out in the specification. The invention also includes pharmaceutical compositions incorporating a formula I compound or a salt thereof, a process for the manufacture of the said compound, together with intermediates for use in the latter process. ##STR1##