Method for making liposomes of enhanced entrapping capacity toward foreign substances to be encapsulated
US5393530A · kind A · utility
67Cited by
2References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 22, 1992 |
| Grant date | Feb 28, 1995 |
| Priority date | — |
| Expiry date | Jun 22, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1278
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Liposome vesicles are prepared containing water or very dilute solutions encapsulated therein. These "empty" liposomes are suspended in a carrier liquid containing, dispersed therein, substances of interest to be loaded into the vesicles and incubated for a period of time at temperatures above the lipids transition temperature, whereby loading by transmembrane permeation occurs in high yields.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.