Patent · US Expired

Constitutent layer harvesting from a centrifuged sample in a tube

US5393674A · kind A · utility

138Cited by
20References
4Claims
0Family size

Inventors

Key dates

Filing dateMar 8, 1993
Grant dateFeb 28, 1995
Priority date
Expiry dateMar 8, 2013

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/2575
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Constituent layers are harvested from a centrifuged multi-constituent material in an evacuated glass or clear plastic tube which contains a float. When possibly contaminated materials, such as blood, are being tested, the use of an evacuated tube allows the measurements to be made without the technician being exposed to the blood. The tubes are large enough to hold approximately one ml of blood, and are filled with an inert gas at low pressure. The floats are formed with a through bore into which cell bands to be harvested will settle during centrifugation. The cell bands are stabilized by a layer of a flowable material which settles onto the plasma layer during centrifugation and forms a pellicle thereon. The cell layers to be harvested are aspirated from the float bore by way of a hypodermic needle or cannula inserted into the tube and float bore.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.