Patent · US Expired

Intermediates for the synthesis of anthrapyrazolone anticancer agents

US5393886A · kind A · utility

1Cited by
3References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 25, 1993
Grant dateFeb 28, 1995
Priority date
Expiry dateOct 25, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D231/54
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to compounds, including 5-chloro-2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-7-[2,4,6-trimethylphen yl)methoxy]anthra[1,9-cd]pyrazol-6(2H)-one and analogs thereof, which are useful as intermediates for the synthesis of anthrapyrazolone anticancer agents, including losoxantrone. This invention also relates to methods for the synthesis of anthrapyrazolone anticancer agents, including losoxantrone.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.