Process for producing simvastatin and analogs thereof
US5393893A · kind A · utility
21Cited by
3References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 8, 1993 |
| Grant date | Feb 28, 1995 |
| Priority date | — |
| Expiry date | Nov 8, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/025
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is disclosed for the preparation of simvastatin and its analogs through a novel intermediate (III), which enables a selective .alpha. carbon alkylation of the C-8 acyl side chain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.