3,5-di-t-butyl-4-hydroxyphenylmethylhydroxylamines and their derivatives, pharmaceutical compositions, and methods of use therefor
US5393923A · kind A · utility
0Cited by
1References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 12, 1993 |
| Grant date | Feb 28, 1995 |
| Priority date | — |
| Expiry date | Oct 12, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C335/40
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is a novel compound which is a 3,5-di-t-butyl-4-hydroxyphenylmethylhydroxylamine or derivative thereof and a pharmaceutically acceptable acid addition or base salt thereof, pharmaceutical composition and methods of use therefor. The invention compounds are now found to have activity as inhibitors of one or both of cyclooxygenase and 5-lipoxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.