Method for the preparation of arylalkanolamineacylates
US5393924A · kind A · utility
6Cited by
4References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 29, 1994 |
| Grant date | Feb 28, 1995 |
| Priority date | — |
| Expiry date | Apr 29, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C233/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Acylamides or amine acylate salts of arylalkanolamines are prepared by reacting an arylisonitrosoalkanone with hydrogen and a carboxylic acid, carboxylic acid anhydride or carboxylic acid ester or mixture thereof in the presence of a transition metal catalyst; optionally the product is converted to the corresponding arylalkanolamine hydrochloride salt by reaction of the acylamide or amine acylate salt of the arylalkanolamine with hydrogen chloride in a C.sub.1 -C.sub.3 alkyl alcohol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.