Use of thiazoloisoindolinone derivatives as antiviral medicaments

US5397794A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Harald Zilch · Mannheim, DE
• Alfred Mertens · Schriesheim, DE
• Herbert Leinert · Heppenheim, DE
• Ulrike Leser · Munich, DE
• Bernhard König · Bobingen, DE
• Hans Seidel · Tutzing, DE

Key dates

• Filing date: Jul 20, 1993
• Grant date: Mar 14, 1995
• Expiry date: Jul 20, 2013

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P31/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention concerns the use of compounds of the general formula I ##STR1## for the preparation of medicaments for the treatment of viral or retroviral infections, whereby R signifies a hydrogen atom or a straight-chained or branched, saturated or unsaturated alkyl radical with 1-7 carbon atoms, which can possibly be substituted by phenyl, or a phenyl ring which can possibly be substituted one or more times by C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, hydroxyl, trifluoromethyl, methylsulphonyl or halogen, such as fluorine, chlorine or bromine, n stands for the numbers 0, 1 or 2, as well as of their pharmacologically compatible salts or tautomers.