Patent · US Expired

Reaction cell for protein sequencer and the like

US5399317A · kind A · utility

14Cited by
4References
20Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJul 16, 1993
Grant dateMar 21, 1995
Priority date
Expiry dateJul 16, 2013

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01L2300/0877
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present invention comprises a reaction cell for a sequencer and the like which includes a sample carrier assembly having a flexible, resilient spacer with a hole therein for retaining the sample on a membrane, a pair of alumina cells which bracket the spacer, one or more pads or spacers to retain the assembly in a tight fitting relation and a cap to secure the assembly together. The reagents are input and withdrawn from opposite edges of the sample membrane. The present invention has a minimal dead volume as a result of the spacer arrangement. It also permits benchtop sample loading due to the separation of the assembly into a carrier and base housing. The fluid lines are self-sealing to the reaction cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.