Process for the preparation of nitride complexes of transition metals
US5399339A · kind A · utility
10Cited by
4References
23Claims
0Family size
Assignee
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Key dates
| Filing date | Jan 21, 1993 |
| Grant date | Mar 21, 1995 |
| Priority date | — |
| Expiry date | Jan 21, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Process for the preparation of nitride complexes of transition metals for use as radiopharmaceutical products or for the synthesis of novel pharmaceutical products. The process consists in reacting an oxygenic transition metal compound such as 99m.sub.Tc, 186.sub.Re or 188.sub.Re, with a first nitrogenous ligand such as sodium nitride or a nitrogenous compound such as S-methyl, N-methyl dithiocarbazate, and a reducing agent consisting of either tin (II) or a dithionite. The product so obtained can be used for the preparation of radiopharmaceutical products by a reaction with a second ligand such as sodium dithiocarbamate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.