Surface modified anticancer nanoparticles
US5399363A · kind A · utility
451Cited by
12References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 1, 1992 |
| Grant date | Mar 21, 1995 |
| Priority date | — |
| Expiry date | Jul 1, 2012 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Dispersible particles consisting essentially of a crystalline anticancer agent having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm. Anticancer compositions comprising the particles exhibit reduced toxicity and/or enhanced efficacy, and can be administered by IV bolus injection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.