Patent · US Expired

Use of flavone derivatives for gastroprotection

US5399584A · kind A · utility

11Cited by
5References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 10, 1993
Grant dateMar 21, 1995
Priority date
Expiry dateFeb 10, 2013

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/35
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The subject invention relates to methods for preventing or treating damage to the mucosal lining of the gastrointestinal tract of a human or lower animal by administering a safe and effective amount of a compound having the structure: ##STR1## wherein X and Y are each independently selected from O and S; R.sup.1, R.sup.2 and R.sup.3 are each independently selected from hydrogen, hydroxy, halo, unsubstituted or monosubstituted straight or branched C.sub.1 -C.sub.4 alkanyl, and unsubstituted or substituted straight or branched C.sub.1 -C.sub.4 alkanoxy; and each of R.sup.4, R.sup.5, R.sup.6 and R.sup.7 is hydrogen or, if one or more of R.sup.1, R.sup.2 and R.sup.3 is other than hydrogen, each of R.sup.4, R.sup.5, R.sup.6 and R.sup.7 is selected from hydrogen, halo, trifluoromethyl, and unsubstituted straight or branched C.sub.1 -C.sub.4 alkanyl.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.