Patent · US Expired

Color control & stability in acetaminophen

US5399760A · kind A · utility

1Cited by
5References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 11, 1993
Grant dateMar 21, 1995
Priority date
Expiry dateAug 11, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C231/24
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A method is provided for purifying crude N-acetyl-para-aminophenol (APAP) containing color bodies or their precursors, the method comprising: a) forming a solution of the crude APAP; and b) subsequently contacting the solution with substoichiometric quantifies of an acetylating agent for a sufficient period of time to convert said color bodies or their precursors to substantially non-color bodies/stable, colorless substances; said quantities of acetylating agent provided is such that substantially none of the APAP is converted to other compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.