Patent · US Expired

Controlled administration of chemodenervating pharmaceuticals

US5401243A · kind A · utility

57Cited by
12References
16Claims
0Family size

Assignee

Inventor

Key dates

Filing dateApr 12, 1993
Grant dateMar 28, 1995
Priority date
Expiry dateApr 12, 2013

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/4886
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The activity of chemodenervating agents can be ascertained by injecting locally a known quantity of the agent and determining the extent of inhibition of acetylcholine release about the locus resulting therefrom. Inhibition of acetylcholine release is indicative of denervation in a muscle, therefore the extent of inhibition of acetylcholine release is coextensive with the zone of denervation induced by the quantity of the agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.