Patent · US Expired

Cephem compounds

US5401734A · kind A · utility

19Cited by
2References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 20, 1993
Grant dateMar 28, 1995
Priority date
Expiry dateMay 20, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D501/46
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Cephem compounds of the formula: ##STR1## wherein R.sup.1 is amino or a protected amino group, PA1 Z is N or CH, PA1 R.sup.2 is lower alkyl, mono(or di or tri)halo(lower)alkyl, lower alkenyl, lower alkynyl, phenyl, naphthyl, phenyl(lower)alkyl, carboxy(lower)alkyl or protected carboxy(lower)alkyl, and PA1 R is a group of the formula: ##STR2## in which R.sup.3 and R.sup.4 are each lower alkyl, PA2 A is lower alkylene, and PA2 R.sup.5 is hydroxy or a protected hydroxy group; or pharmaceutically acceptable salts thereof show antimicrobial activities and are useful in the treatment of microbial infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.