Substituted pyridines heptenoic acid derivatives, useful for treating arterioscleros, lipopotaemia and the like

US5401746A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Rolf Angerbauer · Wuppertal, DE
• Peter Fey · Wuppertal, DE
• Walter Hubsch · Wuppertal, DE
• Thomas Philipps · Cologne, DE
• Hilmar Bischoff · Wuppertal, DE
• Dieter Petzinna · Mülheim an der Ruhr, DE
• Delf Schmidt · Wuppertal, DE
• Gunter Thomas · Arese, IT

Key dates

• Filing date: Jul 20, 1992
• Grant date: Mar 28, 1995
• Expiry date: Jul 20, 2012

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F7/1804
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel compounds for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis of the formula ##STR1## in which A, B, D and E can have varied meanings, PA0 X is --CH.sub.2 --CH.sub.2 or --CH.dbd.CH--, and PA0 R is ##STR2## wherein R.sup.21 --denotes hydrogen or alkyl and PA0 R.sup.22 --denotes hydrogen, PA1 denotes alkyl, aryl or aralkyl, or PA1 denotes a cation, and their oxidation products.