2-aminocarboxylic acids and their derivatives, processes for their preparation and their use as medicaments

US5401875A · kind A · utility

Assignee

• Godecke Aktiengesellschaft · DE

Inventors

• Uwe Trostmann · Gundelfingen, DE
• Johannes Hartenstein · Kirchzarten, DE
• Claus Rudolph · Denzlingen, DE
• Christoph Schachtele · Glückstadt, DE
• Hartmut Osswald · Völklingen, DE
• Gunter Weinheimer · Denzlingen, DE

Key dates

• Filing date: Apr 22, 1991
• Grant date: Mar 28, 1995
• Expiry date: Apr 22, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C229/36
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention concerns 2-aminocarboxylic acids and derivatives of formula ##STR1## processes for their preparation, as well as medicaments containing them for the inhibition of protein kinase C and thus for the prevention and/or treatment of heart and blood vessel diseases, such as thromboses, arterioscleroses, hypertension, of inflammatory processes, allergies, cancers, and certain degenerative damages of the central nervous system.