Patent · US Expired

Spectrophotometric examination of tissue of small dimension

US5402778A · kind A · utility

179Cited by
21References
33Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJan 19, 1993
Grant dateApr 4, 1995
Priority date
Expiry dateJan 19, 2013

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2201/0696
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A system for examination of a relatively small volume of biological tissue of interest using visible or infra-red radiation includes a spectrophotometer, an optical medium of a relatively large volume having selectable scattering and absorptive properties, and a processor adapted to determine a physiological property of the examined tissue. The spectrophotometer includes a light source for introducing radiation at an optical input port, a detector for detecting radiation that has migrated through a path from the input port to an optical detection port, and a processor for evaluating changes between the introduced and the detected radiation. The biological tissue of interest is positioned into the photon migration path inside the optical medium to create a tissue-medium optical path. The optical medium is adapted to limit substantially escape of photons from the tissue. The processor determines a physiological property of the tissue based on the detected optical property of the tissue-medium optical path and the scattering or absorptive properties of the selected optical medium. Alternatively, the system can match the optical properties of the medium to the optical properties of the…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.