Melt granulated compositions for preparing sustained release dosage forms
US5403593A · kind A · utility
112Cited by
9References
23Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 31, 1992 |
| Grant date | Apr 4, 1995 |
| Priority date | — |
| Expiry date | Mar 31, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2095
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Therapeutically active sustained release dosage forms are described which are prepared from compositions which comprise (A) a hydrophilic cellulose ether polymer or mixtures thereof as a binder matrix material, (B) a granulating medium selected from the group consisting of a lipid component, polyethylene glycol polymers, and mixtures thereof, said granulating medium having a melting range higher than about 30.degree. C., and (C) a therapeutically active medicament, said components being in melt association. The compositions are prepared by a melt granulation process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.