Vitamin D.sub.3 analogues
US5403832A · kind A · utility
6Cited by
3References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 2, 1994 |
| Grant date | Apr 4, 1995 |
| Priority date | — |
| Expiry date | Aug 2, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/532
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A vitamin D.sub.3 analogue which includes a hydroxyalkyl substituent in the 1-position and a modified D-ring side chain is described. This novel compound is a potent anti-proliferative substance with activity comparable to that of calcitriol but with a vitamin D.sub.3 receptor binding rating of approximately 10.sup.-3 compared to that of calcitriol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.