6-0-methylerythromycin A derivatives
US5403923A · kind A · utility
37Cited by
2References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 20, 1993 |
| Grant date | Apr 4, 1995 |
| Priority date | — |
| Expiry date | May 20, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H17/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention provides 6-O-methylerythromycin A derivatives represented by the following formula ##STR1## (wherein R.sup.1 and R.sup.2 each represent a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, and A represents a nitrogen atom or a N.fwdarw.O group) and their pharmaceutically acceptable salts. The erythromycin A derivatives have a strong antimicrobial activity against Gram-negative bacteria and have a much stronger activity against Gram-positive bacteria than previously known compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.