Means for containing active substances, having a shell of hydrophilic macromolecules, active substances and process for preparation thereof

US5405616A · kind A · utility

Assignee

• ALFATEC-Pharm GmbH · DE

Inventors

• Jens-Christian Wunderlich · Heidelberg, DE
• Ursula Schick · Schriesheim, DE
• Jurgen Freidenreich · Schriesheim, DE
• Jurgen Werry · Ludwigshafen, DE

Key dates

• Filing date: Apr 30, 1992
• Grant date: Apr 11, 1995
• Expiry date: Apr 30, 2012

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61Q17/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention is directed to exactly dosable molded particles, for example granulates or pellets comprising hydrophilic macromolecules, active materials and additionally further pharmaceutically acceptable skeleton formers and additives wherein the active substance is provided to the matrix, dissolved, suspended or emulsified and a new process for the preparation of such molded particles wherein the process is particularly economically and ecologically unburdensome, as well as the use of such molded particles as pharmaceuticals in which the bioavailability, shelf life, and acceptability ar improved. Furthermore, by means of the molded particles of the present invention, mixtures, intermediates, and end products may be provided for the fields of pharmacy, cosmetics, diagnostics, and analysis and dietetics (health care).