Chemical compounds
US5405990A · kind A · utility
10Cited by
1References
13Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jul 22, 1993 |
| Grant date | Apr 11, 1995 |
| Priority date | — |
| Expiry date | Jul 22, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C311/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Prodrugs, of generic formula I, are disclosed for use in antibody directed enzyme prodrug therapy (ADEPT). The prodrugs are substrates for carboxypeptidase G2 (CPG2) and yield more active cytotoxic drugs than known products of CPG2 catalyzed reactions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.