Filter medium having a limited surface negative charge for treating a blood material
US5407581A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 17, 1993 |
| Grant date | Apr 18, 1995 |
| Priority date | — |
| Expiry date | Mar 17, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S210/929
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Disclosed is a filter medium for treating a blood material selected from the group consisting of a leukocyte-containing suspension and plasma, comprising a polymeric, porous element having, in a surface portion thereof, a negative charge and having a surface electric charge of not smaller than -30 .mu.eq/g of the polymeric, porous element. The filter medium and an apparatus having the filter medium packed in a casing having an inlet and an outlet, can be advantageously used for treating a blood material, for example, for separating leukocytes from a leukocyte-containing suspension including whole blood, for blood dialysis or for removing undesired proteinous substances and the like from whole blood or plasma by adsorption-filtration, while effectively controlling a concentration of bradykinin (which is causative of anaphylactic reactions) in a treated blood to a level not exceeding 4,000 pg/ml.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.