Process for the preparation of azo-and /or disulfide polymer matrix drug delivery system for the site specific delivery of an active agent in the colon
US5407682A · kind A · utility
6Cited by
4References
12Claims
0Family size
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Key dates
| Filing date | Sep 9, 1992 |
| Grant date | Apr 18, 1995 |
| Priority date | — |
| Expiry date | Sep 9, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G75/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Azo-and/or disulfide-containing polymers for use as drug delivery systems having site-specific release of the drug in the colon are obtained by polycondensation or polyaddition of an azo- and/or polysulfide disulfide containing a, w-dihydroxy or diamino reagent with a suitable a, w-difunctional dicarboxylic acid; disocyanato-, disulfide comonomer. The resulting reduction sensitive polymers are linear macromolecules containing an azo and/or a disulfide bond in their polymer backbone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.