Patent · US Expired

Pyrrolidine compounds which are useful as thromboxane AZ-inhibitors

US5407946A · kind A · utility

5Cited by
1References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 14, 1994
Grant dateApr 18, 1995
Priority date
Expiry dateJun 14, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D401/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Components of formula (I): ##STR1## in which: R.sub.1 represents optionally substituted phenylsulfonyl, naphthylsulfonyl, quinolyl, or isoquinolyl, PA1 R.sub.2 represents hydrogen, optionally substituted phenyl, or optionally substituted 3-pyridyl or 2-pyridyl, PA1 R.sub.3 represents ##STR2## in which m is equal to 2, 3, or 4; n is equal to 4, 5, 6, or 7; and R represents hydrogen or alkyl, as thromboxane A.sub.2 receptor inhibitors or thromboxane A.sub.2 -synthase inhibitors, and pharmaceutical compositions containing the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.