Antithrombotic treatment with calix(n)arene compounds
US5409959A · kind A · utility
13Cited by
1References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 6, 1992 |
| Grant date | Apr 25, 1995 |
| Priority date | — |
| Expiry date | Aug 6, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/3882
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of inhibiting thrombus formation in a mammalian subject. The method involves administering to the subject a therapeutically effective dose of a calix(n)arene compound derivatized, at its ring positions meta to the bridge attachments to the ring, with polar substituents having terminal sulfonate groups, including esters and amides which are cleavable in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.