Magnetic microparticles
US5411730A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 20, 1993 |
| Grant date | May 2, 1995 |
| Priority date | — |
| Expiry date | Jul 20, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Superparamagnetic particles are provided for medical applications including hyperthermia techniques, localized heating and tissue-specific release of therapeutic agents, and magnetic resonance imaging contrast enhancement, comprising superparamagnetic iron oxide and a polymer such as dextran at a ratio of about 0.5 to 0.1 w/w of polymer to iron. The particles display at least one of the following magnetic properties: (a) specific power absorption rate greater than 300 w/g Fe; (b) initial magnetic susceptibility greater than 0.7 EMU/g Fe/Gauss; and (c) magnetic moment greater than 10.sup.-15 erg/Gauss.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.