Hepatoma treatment with somatostatin analogs
US5411943A · kind A · utility
8Cited by
1References
28Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 25, 1992 |
| Grant date | May 2, 1995 |
| Priority date | — |
| Expiry date | Feb 25, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/6555
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for treating liver cancer in a mammalian subject. The method includes administering to the subject a composition which contains a therapeutically effective amount of an octapeptide of the following formula: ##STR1## wherein, A.sub.1 is D-.beta.-Nal or D-Phe; A.sub.2 is Phe, pentafluro-Phe, or p-substituted X-Phe where X is a halogen, NH.sub.2, NO.sub.2, OH, or C.sub.1-3 alkyl; A.sub.3 is Thr, Ser, Phe, Val, .varies.-aminobutyric acid, or Ile; A.sub.4 is Thr, .beta.-Nal, or Trp; and Y is NH.sub.2 or OH; or a pharmaceutically acceptable salt or complex thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.