Patent · US Expired

Ocular cyclosporine composition

US5411952A · kind A · utility

102Cited by
18References
12Claims
0Family size

Assignee

Inventor

Key dates

Filing dateFeb 6, 1990
Grant dateMay 2, 1995
Priority date
Expiry dateFeb 6, 2010

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P37/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Cyclosporine compositions for topical ophthalmic use for treatment of immune disorders, to enhance or restore tear production, and to enhance or effect normal healing of the surface of the eye, containing cyclosporine dissolved in corn oil. The composition may further include antioxidants, lubricants, antibiotics, antifungals, antivirals, pilocarpine, vasoconstrictors, surfactants, wetting agents, anti-inflammatory agents (i.e. corticosteroids), preservatives, mucolytic agents (i.e. bromhexine, acetylcysteine), as well as other compounds. The preferred composition is 2% cyclosporine, 1 mole % alpha tocopherol and 0.005% methyl paraben in corn oil.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.