Method of preparing vicinal aminoalcohols
US5412119A · kind A · utility
32Cited by
2References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 1, 1993 |
| Grant date | May 2, 1995 |
| Priority date | — |
| Expiry date | Feb 1, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is concerned with the preparation of N-substituted vicinal aminoalcohol derivatives from the corresponding hydroxyl-protected cyanohydrin derivatives by successive partial reduction, transimination using a primary amine, reduction of the resulting imine and optional removal of the hydroxyl-protecting group. The products are obtained either as a racemate or in an optically pure form, depending upon the stereochemical composition of the starting cyanohydrin derivatives. The present invention is also concerned with certain new enantiomerically pure hydroxyl-protected vicinal aminoalcohols.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.