Process for the preparation of 4-hydroxy-3[2H]furanones
US5412121A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 8, 1993 |
| Grant date | May 2, 1995 |
| Priority date | — |
| Expiry date | Dec 8, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/60
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is provided for the preparation of 5-alkyl-4-hydroxy-3[2H]furanones and/or 2,5-dialkyl-4-hydroxy-3[2H]furanones, wherein each alkyl group independently has one to six carbons, comprising PA1 (a) saponifying an ester selected from the group of 3,4-dihydroxyfurans substituted at the 2- and/or 5-position with one or two carbalkoxy groups, wherein each alkoxy group independently contains one to six carbon atoms, and optionally substituted at the 2- or 5-position with an alkyl group with one to six carbon atoms, or tautomeric forms or keto-enol isomers thereof, PA1 (b) treating with one or two alkylation reagents which independently may have one to six carbon atoms, and PA1 (c) subsequently recovering the 5-alkyl-4-hydroxy-3[2H]furanones and/or 2,5-dialkyl-4-hydroxy-3[2H]furanones.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.