Patent · US Expired

Process for preparing diprotected 2,3-hydroxymethyl cyclobutanol

US5412134A · kind A · utility

3Cited by
5References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 26, 1992
Grant dateMay 2, 1995
Priority date
Expiry dateMay 26, 2012

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C67/29
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The protected cyclobutanone of the formula ##STR1## is treated with a dialkylaluminum chloride, an alkylaluminum dichloride, a trialkylaluminum compound, diphenylsilane in the presence of tris(triphenylphosphine) rhodium (I) chloride, or iridium tetrachloride to yield the corresponding diprotected cyclobutanol. This compound is useful as an intermediate in the preparation of antiviral agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.