Device for the purification of synthetic oligonucleotides
US5413762A · kind A · utility
7Cited by
2References
9Claims
0Family size
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Key dates
| Filing date | Nov 29, 1993 |
| Grant date | May 9, 1995 |
| Priority date | — |
| Expiry date | Nov 29, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A device for the purification of synthetic oligonucleotides, characterized by comprising means for switching between purification with an affinity column which recognizes trityl groups, in cases where trityl groups are bonded, and purification with a disposable stepwise reverse phase chromatography column in cases where no trityl groups are bonded. The device makes it possible for any person to easily perform high-degree purification, simply by setting the synthesized oligonucleotides. Furthermore, it accomplishes both a method using an affinity column cartridge and a method for purification by HPLC.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.