Process for selecting an enantiomer of a hydroxy lactone using pseudomonas lipase
US5413935A · kind A · utility
3Cited by
3References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 24, 1993 |
| Grant date | May 9, 1995 |
| Priority date | — |
| Expiry date | Mar 24, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/877
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An enantiomerically pure compound of the formula ##STR1## is prepared when the associated racemic mixture is reacted with an acrylating agent R.sup.3 --C(O)--O--R in the presence of a microorganism or enzyme derived therefrom capable of catalyzing transesterification of an alcohol. X.sup.1 and X.sup.2 are each independently halogen, R is alkyl, R.sup.1 and R.sup.2 are each independently alkyl, cycloalkyl, aralkyl or aryl and R.sup.3 is alkyl, cycloalkyl, aryl or aralkyl.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.