1,4-benzothiazepine derivatives
US5416066A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 25, 1993 |
| Grant date | May 16, 1995 |
| Priority date | — |
| Expiry date | Jun 25, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An object of the invention is to provide compounds having a myocardial KD (Kinetic cell death)-inhibiting effect without being accompanied by a cardiodepressant effect. A 1,4-benzothiazepine derivative represented by the following Formula [I]: ##STR1## wherein each of substituent groups is defined as follows: R represents H or a C.sub.1 -C.sub.3 lower alkoxy group; X represents O or H.sub.2 ; n represents 1 or 2; R.sup.1 represents H, a substituted phenyl group wherein the substituent group is OH or a C.sub.1 -C.sub.3 lower alkoxy group, ##STR2## a C.sub.1 -C.sub.3 lower alkoxy group, ##STR3## wherein R.sup.2 represents a C.sub.1 -C.sub.3 acyl group, and ph represents a phenyl group, or a pharmaceutically acceptable salt thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.