Fluid resuscitation
US5416078A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 25, 1992 |
| Grant date | May 16, 1995 |
| Priority date | — |
| Expiry date | Nov 25, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/62
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to fluid resuscitation of the human or animal body by administration of deferoxamine (DFO) and a water-soluble biopolymer. The DFO and the biopolymer are preferably bonded together. The biopolymer may be a polysaccharide or a protein. The DFO and the biopolymer are preferably formulated as an aqueous solution suitable for oral administration. The fluid resuscitation may be effected for ameliorating systemic oxidant injury occurring during ischemia and subsequent reperfusion. The fluid resuscitation may be indicated in treatment of burn injury, lung injury caused by inhalation of hot and/or toxic substances, such as smoke derived from combustion, hemorrhagic shock and other types of trauma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.