Process for inactivating the biological activity of DNA

US5417862A · kind A · utility

Assignee

• Dr. Karl Thomae GmbH · DE

Inventors

• Klaus Bergemann · Biberach, DE
• Georg Bader · Birkenhard, DE
• Wolfgang Berthold · Biberach, DE
• Rolf-Gunter Werner · Biberach, DE

Key dates

• Filing date: Sep 8, 1992
• Grant date: May 23, 1995
• Expiry date: Sep 8, 2012

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N1/08
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A process for inactivating the biological activity of DNA, especially recombinant DNA, is disclosed. The process includes the step of heating the DNA at 60.degree. to 100.degree. C. in the presence of an acid other than percarboxylic acid at a concentration of at least 0.2 mM and a pH value of maximum 4, preferably 3.