Patent · US Expired

Antibody testing system

US5419870A · kind A · utility

6Cited by
5References
8Claims
0Family size

Assignee

Inventor

Key dates

Filing dateNov 23, 1992
Grant dateMay 30, 1995
Priority date
Expiry dateNov 23, 2012

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/805
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

A device for performance of ligand-receptor assay methods for determining the presence of a liquid. The preferred ligand-receptor pair are antigen-antibody pairs. The device has a membrane having the receptor physically bound to its surface. The membrane is disposed at the top of a body member, and is affixed thereto by means for attaching, which is preferably a cap with a funnel depression. A porous means is disposed below the membrane to absorb liquid. Substantially all of the top surface of the membrane is exposed. The receptor site typically occupies only a portion of the top of the membrane, and in a preferred embodiment, a funnel member releasably attaches to the cap, thereby conveying the sample through only that area of the membrane having the receptor site. The device has a piston means disposed inside the body member, and in air-tight seal with the body member. Means to actuate the piston means are disposed outside the body member. The piston means creates a region of reduced pressure to urge the sample through the membrane.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.