Process for separation of enantiomeric 3-mercapto-2-substituted alkanoic acid using lipase P30 and synthesis of captopril type compounds
US5420037A · kind A · utility
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4Claims
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Key dates
| Filing date | Jan 12, 1994 |
| Grant date | May 30, 1995 |
| Priority date | — |
| Expiry date | Jan 12, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P11/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
S-enantiomers of the formula ##STR1## result from the reaction of a racemic form of compound I with an alcohol in the presence of an enzyme capable of selectively esterifying the R-enantiomers of the racemic compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.