Quinazolinones substituted with phenoxyphenylacetic acid derivatives
US5420133A · kind A · utility
31Cited by
11References
14Claims
0Family size
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Key dates
| Filing date | Mar 19, 1993 |
| Grant date | May 30, 1995 |
| Priority date | — |
| Expiry date | Mar 19, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/505
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Phenoxyphenylacetic acids and derivatives of general structural formula I ##STR1## have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, inflammatory diseases, Raynaud's disease, and endotoxic shock, and asthma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.