Difluorinated quinolones useful for treating bacterial infections
US5420140A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Dec 8, 1992 |
| Grant date | May 30, 1995 |
| Priority date | — |
| Expiry date | Dec 8, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method of treating bacterial infections in warm-blooded animals comprising administering to warm-blooded animals an antibactericidally effective amount of at least one compound of the formula ##STR1## wherein R is ##STR2## Y is selected from the group consisting of lower alkyl, lower alkenyl, phenyl optionally substituted with 1 to 3 members of the group consisting of halogen, lower alkyl, --NO.sub.2, --CF.sub.3 and alkoxy carbonyl, X is oxygen and R.sub.1 is selected from the group consisting of methyl, fluoromethyl, vinyl, phenyl and ##STR3## wherein Z is halogen and p is 1, 2 or 3 and its non-toxic, pharmaceutically acceptable salts with a base or acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.