Patent · US Expired

Inhibitors of farnesyl protein transferase or prodrugs thereof

US5420157A · kind A · utility

1Cited by
4References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 16, 1991
Grant dateMay 30, 1995
Priority date
Expiry dateDec 16, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12R2001/645
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

This invention relates to pharmaceutical compounds of structural formulae (I) and (II): ##STR1## and compositions and methods of treatment utilizing these compounds to inhibit farnesyl protein transferase and farnesylation of the oncogene protein Ras.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.