Process for the continuous reaction of halogenopyrimidines with amines

US5420255A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Siegbert Arnold · Bonn, DE
• Hans-Georg Frosch · Cologne, DE
• Manfred Hoppe · Kürten, DE
• Wolfgang Mullers · Bensberg, DE
• Richard Sommer

Key dates

• Filing date: Feb 22, 1994
• Grant date: May 30, 1995
• Expiry date: Feb 22, 2014

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01J2219/00177
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the continuous reaction of halogenopyrimidines with amines, a halogenopyrimidine and an aqueous amine solution or suspension being passed into a reactor and the reaction product being subsequently conducted away, is described, characterized in that the starting materials are introduced into the reactor simultaneously and continuously with intensive mixing.