Patent · US Expired

Process for the preparation of 2-substituted 5-alkyl-pyridines

US5420284A · kind A · utility

1Cited by

19References

8Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Helmut Kraus · Cologne, DE
Alexander Klausener · Neunburg vorm Wald, DE
Hauke Furstenwerth · Leverkusen, DE

Key dates

Filing date	Oct 7, 1993
Grant date	May 30, 1995
Priority date	—
Expiry date	Oct 7, 2013

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D213/73
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The title compounds of the formula ##STR1## can be prepared by cyclization of aminomethylenated 2-pentenoic acid derivatives of the formula ##STR2## where R, X, R.sup.1, R.sup.2 and Z have the meaning given in the description, in the presence of acids or ammonia. Preferably, aminomethylenated pentenoic acid derivatives are employed which can be prepared from pentenoic acid derivatives of the formula EQU R--CH.sub.2 --CH.sub.2 --CH.dbd.CH--Z (III) or EQU R--CH.sub.2 --CH.dbd.CH--CH.sub.2 --Z (IV) with ortho-amides of the formula ##STR3## The meanings of A and B are also given in the description.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.