Inhibitors of farnesyl-protein transferase
US5420334A · kind A · utility
12Cited by
13References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 4, 1994 |
| Grant date | May 30, 1995 |
| Priority date | — |
| Expiry date | Apr 4, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FPTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting famesyl-protein transferase and the famesylation of the oncogene protein Ras.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.