Formulation of and dehydration of hydroxylated diphenyl acetylenes
US5420361A · kind A · utility
2Cited by
12References
7Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 10, 1994 |
| Grant date | May 30, 1995 |
| Priority date | — |
| Expiry date | May 10, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/874
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The production of cis-dihydrodiol compounds of the formula ##STR1## where n is 0 or 1 (preferably 0) by the microbial oxidation of a diphenylaceylene compound of the formula ##STR2## using a mutant of a Pseudomonas bacteria at 25.degree. to 35.degree. C. and pH 6-8 is disclosed. The cis-dihydrodiol compound is in turn treated with an aqueous solution of a base to produce a corresponding 3-hydroxydiphenylacetylene compound or with an aqueous solution of an acid to produce a corresponding 2-hydroxyacetylene compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.